The function of a growth hormone is related to the beauty, vitality, energy, resilience and young look of a person besides helping the person to grow taller.
However, if the amount of HGH in the body exceeds the normal level, it may result in aging, wrinkled skin, bone denseness, weight gain, acne, low sexual stamina, and loss of lean muscles.Growth Hormone Effects:This hormone has two characteristic types of effects:
Direct Effects: When a growth hormone, which enables a person to grow taller binds to receptors present on the target cells, direct effects are produced. For instance, adipocytes (fat cells) possess growth hormone receptors.
When the HGH binds, it not only increases triglyceride breakdown, but also decreases the accumulation and intake of circulating lipids.
Indirect Effects: These effects occur due to an insulin-like growth factor (IGF). The liver and other body tissues secrete this hormone in the presence of the growth hormone. Individuals grow taller due to the IGF acting on the growth hormone’s target cells.
Effects On Growth: Proper growth is an extremely complex process and needs a unified hormone action. The most important role of HGH, while enabling an individual to grow taller is to increase the liver secretion of IGF.
This insulin-like growth factor stimulates the development of cartilage cells (chondrocytes) that help in bone growth.IGF also helps in the growth of muscles apart from making a person grow taller.
It increases the development and differentiation of myoblasts and promotes protein synthesis along with the uptake of amino acids in muscle and additional body tissues.
Protein Metabolism: Growth hormone promotes the formation of protein in several tissues, so that a person can grow taller. This results in increased protein synthesis and amino acid uptake and reduced protein oxidation.
Fat Metabolism: Apart from helping a person to grow taller, the growth hormone increases fat utilization by increasing the process of oxidation in fat cells and promoting triglyceride breakdown.
Carbohydrate Metabolism: Human growth hormone helps in maintaining a normal range of blood glucose level. It decreases the glucose uptake by insulin in peripheral body tissues and stimulates the synthesis of glucose.
Excess of HGH may also lead to hyper-insulinemia.Disorders Caused By The Growth Hormone:
Hypoglycemia: If the human growth hormone produces an excessive amount of insulin, the blood glucose level may decrease. This may lead to diabetic coma. However, there are several HGH drugs available at present that decrease the risk of hypoglycemia.
Carpal Tunnel Syndrome: This is caused some of the nerves in the wrist get constricted. It results in hand movement loss.
Extended Belly: This is a common disorder caused by the deficiency of growth hormone. It is usually noticed in in body builders.
Joint Pain: Sometimes individuals may experience joint pain, as the growth hormone enables a person to grow taller. However, it is a temporary effect.
Other disorders caused by the Human Growth Hormone include damage to the thyroid gland or liver, excessive water retention, acromegaly, and enlargement of the heart.
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